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920-340 - Nortel Software Communication System 500 Rls.2.0 Config - BrainDump Information

Vendor Name : Nortel
Exam Code : 920-340
Exam Name : Nortel Software Communication System 500 Rls.2.0 Config
Questions and Answers : 57 Q & A
Updated On : Click to Check Update
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best DNA verify for 2021: AncestryDNA vs. 23andMe and more | 920-340 real questions and Questions and Answers

pushed through bigger visibility, decrease costs and enhancing science, DNA trying out has entered the mainstream over the past two decades. A DNA examine can assist you establish shut spouse and children the entire approach lower back to your earliest ancestors, that could kickstart or increase your figuring out of your household heritage. though a controversial and thorny subject, some assessments claim to exhibit your "ethnicity," and a few functions can shed light to your genetic predisposition for diseases and physiological features ranging from eye colour to your tolerance for cilantro. 

back within the aughts, a homemade DNA examine cost about $1,000. Now, trailblazers akin to 23andMe and Ancestry and upstarts together with living DNA offer a complicated evaluation of your genetic make-up for a fraction of that. And when you are searching around Black Friday, on national DNA Day or all through the break season, you can be able to ranking critical bargain. 

Now enjoying: Watch this: right here's how genetic genealogist CeCe Moore finds expertise...


There are three types of DNA tests -- each with its personal certain strengths, obstacles and rationales.

  • An autosomal DNA look at various is the most efficient investment for many rookies; it may possibly determine relatives between five and 7 generations again, across each maternal and paternal lines. 
  • handiest men can conveniently use a Y-DNA verify, which identifies male spouse and children on the paternal line reaching lower back 60,000 years; if you are looking to hint the historical past of your family's surname, here is the examine to make use of. 
  • And mitochondrial DNA checking out, often known as mtDNA trying out, can determine genetic relationships on a maternal line from as much as one hundred fifty,000 years ago; each guys and girls can take this class of check. 
  • when you've been proven, each enterprise will existing you with an evaluation of your geographical foundation; some claim to be in a position to pinpoint a particular country, city and even "tribe." Some will additionally serve up "matches" from their DNA databases, so they can offer you a head delivery on connecting with possible loved ones, and offer some diploma of household tree analysis help. AncestryDNA, for example, presents a subscription carrier that contains entry to hundreds of databases containing beginning, death and marriage bulletins, census files, newspaper archives and other ancient records. 

    Some companies sell tests designed for specific ethnicities or really good kits that claim to shed easy on your most efficient skin care routine or weight; others present exams designed to determine the genetic makeup of your cat or dog. The experts I spoke to were doubtful of the efficacy and value of these tests and informed warding off them.

    if you subscribe to just one CNET publication, this is it. Get editors' correct picks of the day's most entertaining reports, information stories and videos.

    although there's no blood concerned with modern DNA trying out -- you either swab the inside of your cheek or fill a small look at various tube with your saliva -- there are a lot of motives to be leery of the organizations that sell these kits. Your success in DNA look at various family tree is essentially based on presenting totally personal suggestions about yourself and your spouse and children -- out of your genetic facts to your mother's maiden name, that common cornerstone of password protection. 

    issues over information privacy and safety are well-based, and consultants warn that regulation -- specially within the US -- lags a ways at the back of the know-how. and you should still be aware of that some DNA checking out companies may also share facts with pharmaceutical companies and law enforcement organizations. final analysis: think significantly before volunteering tips about your fitness historical past and familial connections to any DNA checking out company or organization. 

    examine more: sooner or later, not even your DNA could be sacred

    DNA checking out, and family tree extra widely, involves an advanced mixture of genetics, possibilities and guesswork. The a number of DNA testing capabilities use different labs, algorithms, machine and criteria to research your genetic cloth; even though you should expect some diploma of overlap between analyses from distinct groups, they can also fluctuate vastly. there may be additionally a component of essential mass -- the better the business's database, the larger the pattern they use to analyze your results, and the more correct your test outcomes may still be. 

    We tried some of the suitable DNA trying out capabilities, assessing the breadth and depth of their choices, methodologies, attractiveness and cost. Take a look at our thoughts under. And in case you've taken any of those DNA assessments, inform me about your event with it in the comments below.

    attempting to find greater in-depth data on DNA testing capabilities in typical? leap to our DNA test package explainer.


    headquartered in 2006, 23andMe is one of the pioneers of DNA checking out for consumers. In 2017 it grew to be the first such provider to win the FDA's approval as a risk screener for ailments. It has turn into one of the vital popular DNA checking out agencies -- and neatly-funded, on account that taking in a $300 million stake from GlaxoSmithKline, which uses the business's consumer statistics to research and design new drugs. still, the business lately introduced a circular of layoffs, citing a slowdown within the DNA checking out market possible brought about with the aid of increasing issues about privacy.

    23andMe segments its analysis into three main classes -- health, ancestry and qualities. The primary ancestry and features look at various, which is now on sale for $seventy nine, contains an analysis of your genetic makeup including your regions of foundation, maternal and paternal lineage and Neanderthal ancestry. once you choose in, the company's in shape database -- which has more than 10 million profiles -- will establish and present to join you with people who share a DNA in shape with you.

    The company's DNA health verify, which is on sale for $129, provides tips about your genetic predisposition for late-onset Alzheimer's, Parkinson's and different illnesses. The carrier additionally comprises analysis of your provider status as a possible genetic carrier for problems like Cystic Fibrosis and Sickle cellphone Anemia as well as indications for lactose intolerance and other "health" considerations. The VIP fitness and Ancestry equipment, currently on sale for $429, offers priority lab processing, top rate consumer guide and a personalized walkthrough of your consequences. 

    I found 23andMe's web site and cellular app very handy to navigate and brimming with unique, understandable assistance about both my ancestry and health as well because the science of genetics and family tree. The main dashboard offers intuitive links to exploring your ancestry, gaining knowledge of about the genetic hazards for fitness conditions, constructing out a household tree and connecting with relatives. among the entire DNA tests i attempted, 23andMe delivered the most efficient introduction to my fresh and historical genealogy together with evaluation of my genetic health. The most effective real disadvantage is that it does not offer integrated access to historical files.

    23andMe does supply handy entry to a full range of privateness preferences and consent alternatives, although. (That stated, 23andMe's phrases of carrier and privacy observation is among the most huge, exceeding 20,000 words.) that you can ask the enterprise to store your saliva pattern indefinitely for future testing or have them discard it. Having signed off once I first signed up, I as a result changed my mind about giving the enterprise permission to share my statistics with researchers backyard of 23andMe, and become in a position to retract my consent with the click of a button.

    examine greater: Ancestry vs. 23andMe: Which DNA checking out equipment is top-quality for tracing your family unit background?

    Ian Knighton/CNET

    based in Utah in the Nineties, Ancestry.com -- the mother or father enterprise of AncestryDNA -- begun out as a publishing and family tree enterprise. when you consider that then, it has had a a bit of tumultuous company existence, having been bought, offered, publicly traded and then bought via private equity corporations.

    The company's fundamental DNA kit service, at the moment on sale for $fifty nine, provides you with an "ethnicity estimate" derived from its proprietary sequencing strategies. it be noteworthy that the enterprise's genetic trying out, which is outsourced to Quest Diagnostics, is diverse from most different corporations that use paternal Y chromosome and/or maternal mitochondrial DNA methodologies, and less is time-honored concerning the specific standards it makes use of. 

    That stated, AncestryDNA says its database includes more than 18 million profiles, making it the biggest of all of the testing features. The company also keeps a magnificent tool for browsing through lots of of old doc databases -- but any noticeable analysis will without delay carry you to a paywall. Ancestry's databases are extra bolstered by means of its partnership with FamilySearch.org, a genealogical data web site run through the Mormon church.

    An entry-level membership, which provides entry to more than 6 billion records within the US, costs $99 for six months or $25 per month, after a free two week trial. The "World Explorer" membership, for $40 per 30 days, broadens your entry to the business's 27 billion foreign records, and the "All access" tier, beginning at $50 monthly, includes unlimited entry to Ancestry's historic and modern database of more than 15,000 newspapers and military statistics from everywhere. 

    AncestryDNA presents a personalized health report with "actionable insights," access to genetic counseling resources, a web device to support you map your household's fitness over generations and, beginning in August 2020, a subsequent-technology sequencing carrier for screening your genetic risk for coronary heart disease, some cancers and blood problems. nevertheless, the outcomes are not diagnostic -- although the look at various result must be authorized by probably the most business's physicians -- and the service does not have FDA approval. For now, 23andMe maintains the competencies when it comes to introductory DNA testing for fitness dangers and genetic screening. but AncestryDNA's service is principally well-proper for leveraging an introductory DNA evaluation into deep old analysis to build out a family tree.

    AncestryDNA means that you can get your full DNA results profile and upload the uncooked statistics into other equipment, and it offers moderately decent control over your privateness preferences, although the options don't seem to be as granular as others. 

    read greater: What AncestryDNA taught me about DNA, privacy and the advanced world of genetic testing


    headquartered in 2000, FamilyTreeDNA offers a complete suite of studies and interactive equipment to analyze your DNA and build a family unit tree. With a reputable declare to "the realm's most complete DNA matching database," FamilyTreeDNA presents all three types of checks -- autosomal DNA, Y-DNA and mtDNA. And it be the only business to personal and function its own checking out facility: The Gene-through-Gene genetic lab, discovered in Houston.

    The company's entry-degree "family unit ancestry" package continually expenses $seventy nine -- but it now on sale for $59. The check results deliver suggestions about your ethnic and geographic origins, identifies talents household and presents access to the business's big DNA database. I paid $275 for a huge DNA examine that covered evaluation of my mtDNA and Y-DNA -- assessments which are at the moment on sale for $ninety nine and $139, respectively, if you happen to purchase them personally -- as neatly as the "household Finder," the business's autosomal test.  

    notwithstanding the consumer interface is slightly extra advanced than what you'll locate on different sites, FamilyTreeDNA offers essentially the most finished suite of introductory tools of any issuer I proven. For every classification of look at various, you are offered with matches -- I acquired greater than 22,000 for my autosomal DNA look at various -- a chromosome browser, migration maps, haplogroups and connections to ancestral reference populations, guidance about mutations and a hyperlink that means that you can down load your raw facts. Suffice to say, there are a lot of threads to pull on to learn about your self, your family and your health. 

    FamilyTree also offers a number of greater-conclusion exams, for those interested in digging deeper, together with more than a few Y-DNA checks so as to hint the direction of your male ancestors and the historical past of your surname. The enterprise additionally permits you to upload raw DNA records files from other services and transfer your autosomal suggestions to its database to expand your universe of fits and relationships. 

    From an information safety and privacy perspective, there are a few issues I find attractive about FamilyTreeDNA. The company does its own DNA trying out in apartment, processing and storing your pattern in its lab. Posted prominently on the front web page of its site is a promise that the enterprise will not ever promote your DNA to 3rd parties. Like most other businesses, however, FamilyTreeDNA may additionally use your aggregate genetic suggestions for inside analysis and might agree to requests from legislation enforcement -- unless you opt out. 

    other DNA checking out alternatives

    The three services above are our excellent decisions for the most effective DNA look at various. but they weren't the only ones we proven. What follows are some extra options, none of which eclipsed the 23andMe, Ancestry or FamilyTreeDNA in any colossal vogue. 

    MyHeritage kit1 MyHeritage

    primarily based in Israel, MyHeritage turned into situated in 2003, and like a few different capabilities profiled right here, started out as a family tree software platform. Over time, it received a few historical databases and at last delivered DNA testing in 2016. (MyHeritage outsources its DNA evaluation to FamilyTreeDNA.) In 2018, MyHeritage experienced a safety breach, exposing the email addresses and hashed passwords of more than ninety two million clients.

    MyHeritage offers a free tier of service that includes some simple family tree-building and entry to excerpts of historical files. It might not get you too some distance. 

    The primary DNA trying out and evaluation carrier, which is now on sale for $forty nine, includes the average fare -- a file of your genetic makeup across the enterprise's 42 supported ethnicities, the identification of household and connections to them where feasible. All things considered, I favorite FamilyTreeDNA's presentation of my DNA suggestions. but MyHeritage highlighted a first cousin residing in the US, with whom I shared about 15% of my DNA, and provided to reveal me her household tree -- if I paid a $209 annual subscription charge. 

    sure, that is expensive -- a free 14-day trial is accessible -- but the business maintains an fantastic on-line database of ancient documents that includes 3.5 billion profiles in addition to suggestions about over 100 million subscribers and their collective 46 million household timber. This colossal database is powered with the aid of Geni.com, a family tree social media web site it truly is additionally MyHeritage's parent company. based on the manhattan instances, Geni.com has assembled "the realm's greatest, scientifically vetted family unit tree." 

    In 2019, MyHeritage launched a health screening check akin to the one provided by using 23andMe. As part of this effort, the enterprise partnered with PWNHealth, a community of US physicians who oversee the procedure. i used to be required to comprehensive a private and family unit health heritage questionnaire -- it turned into 16 questions -- which was then ostensibly reviewed with the aid of a physician. even though the company says it might probably recommend a "genetic counseling" session administered through PWNHealth, my health consequences had been simply delivered along with my ancestry analysis.

    On the plus aspect, i admire MyHeritage's straightforward entry to quite a number understandable privacy preferences. nonetheless, overall, I found MyHeritage's consumer interface a ways much less intuitive and more complex to navigate than others. though the company's providing is large -- it's some of the few to present a comprehensive research database of historical files, DNA analysis and fitness screening -- I found the combination among them to be a bit of clumsy. 

    living DNA living-dna-kitliving-dna-kit residing DNA

    living DNA describes itself as a "client family tree DNA provider that doesn't promote or share valued clientele' DNA or statistics with third parties," which gives you a sense of its priorities -- or, at the least, its feel of valued clientele' issues. LivingDNA's headquarters in the UK may additionally even be an element in its distinctive mission observation, because it's field to the extra stringent information and privateness rules of the GDPR. 

    LivingDNA divides its choices in a distinct approach than others. The $69 autosomal DNA package provides a top level view of your ancestry in 80 geographical regions and assistance about maternal and paternal haplogroups and access to the business's genetic matching device. The $seventy nine "wellbeing kit" comprises experiences about your physiological compatibility with nutrition, foods and undertaking. And the $99 package gives you all of it.

    fresh ancestry results are offered with a breakdown of percent via nation as well as the percentage because of extra precise areas, as smartly because the origin and migration course of haplogroups. In February 2020, LivingDNA brought an African Ancestry DNA verify document that features records on seventy two areas in Africa and, in response to the company, "five instances the element of any other look at various available on the market." The record is purchasable for free to existing purchasers. 

    That mentioned, the enterprise has a very restrained household healthy database; a corporation representative declined to deliver me a particular quantity however said that it contained less than 1 million profiles. My spouse, who took the test, lower back exactly zero suits. So, if you are seeking to identify and make connections with relatives, there are more suitable selections in the market. That noted, LivingDNA has a really strong recognition for each the high-quality of its DNA analysis and privateness phrases among experienced genealogists. 

    For experts best: complete genome sequencing

    There are a few businesses -- together with Full Genomes, Veritas Genetics, Nebula Genomics and Dante Labs -- that can sequence all of your DNA, otherwise known as your genome. This stage of evaluation is applicable for superior clients most effective. not best is it costly -- these tests can run into the hundreds of greenbacks, in some circumstances -- it requires a sophisticated figuring out of each genetics and a number of technical equipment required to discover and interpret your results. 

    The competitively priced whole genome tests charge about $300. for example, Full Genome's 30X look at various -- which scans each focused region of your genome 30 times on general -- is considered the standard for a clinical evaluation. It fees $1,800.

    for most people, the leading purpose for sequencing the entire genome is to dive deep into your genetic health outlook. that you could glean your own chance components for illnesses, drug sensitivities and your repute as a service; that's, what you might flow on to your kids. but there are additionally a variety of functions for advanced genealogical initiatives. 

    All of those efforts can also be undertaken -- to a much less severe diploma -- with one of the greater reasonable options outlined above. however entire genome sequencing provides a enormously more finished, correct and excessive decision evaluation. 

    in case you wish to dip your toe into this realm. you could are looking to birth with Nebula Genomics. you could additionally add an existing DNA sequence from Ancestry or 23andMe's DNA database and get Nebula's experiences at a reduced cost.  

    DNA tests we would keep away from HomeDNA

    HomeDNA sells trying out kits below a number of brands, together with DNA Origins, and has a retail presence at Walmart, CVS, rite support and Walgreens. The enterprise's checks claim to combine genetic analysis and "ancestral tracking" concepts that can establish town or village the place your ancestors originated with a high degree of accuracy. Many experts dispute these claims.

    The company offers a range of ancestry testing capabilities starting at $sixty nine. this is the fee aspect for the maternal and paternal lineage kits and the "Starter Ancestry test," which makes use of DNA markers to advance an estimate of your origins in Europe, Indigenous the usa, East Asia and Sub-Saharan Africa -- and suggests you the contemporary population organizations that share your DNA. The $124 "advanced Ancestry examine" expands the evaluation to eighty,000 autosomal genetic markets, 1,000 reference populations and 41 gene pools. 

    i'll observe that the HomeDNA check equipment contained no warning about no longer ingesting or drinking for any duration of time in advance of taking the check -- unlike each different kit I used. And of the four swabs the company despatched, one broke. The examine kit just didn't appear as carefully hygienic because the others.

    For $199, HomeDNA claims that the Asian edition of its GPS Origins Ancestry check can analyze 17 Asia-particular gene pools and a whole lot of Asia-certain reference populations. moreover a $164 paternity package, the company additionally sells numerous certain kits to investigate your sensitivities to selected animals and foods, one to assist you obtain a fit weight, and yet another that guarantees to "free up your dermis's full potential." 

    For $39, the enterprise will assist you to upload a raw facts file from another DNA trying out service and pinpoint your origin to a specific town or city. There are additionally kits to help you determine you display your dog or cat for genetic ailments and traits. 

    however this company would not have a sterling acceptance in the genetic family tree world. after we lately spoke with Debbie Kennett, a genetic genealogist from school school London, she referenced the company's notoriety for providing "bizarre effects" and expressed doubt in regards to the efficacy of its really expert checks for specific ethnic organizations. HomeDNA didn't reply to CNET's inquiry about its checking out technique or effects.

    And the HomeDNA studies do not stack up notably well in opposition t those back through other corporations. effects are summarized on a single webpage, notwithstanding you also get a PDF that certifies that you have "gone through DNA trying out" and shows the continents and countries where your DNA originates. The enterprise additionally throws in a boilerplate 20-web page explainer about DNA science and expertise. HomeDNA does not offer entry to any matching databases -- so there's no obvious subsequent step or any actionable statistics that comes with your results. Given this, i'd advocate selecting a special DNA testing provider.  

    African Ancestry

    Claiming to have the most finished database of African lineages, African Ancestry promises to trace its customers' ancestry back to a selected nation and determine their "ethnic community starting place." but a few skilled genealogists have mentioned issues with this business's marketing claims and science. 

    not like most other businesses, African Ancestry would not present an autosomal DNA test. as an alternative, it offers an mtDNA check or a Y-DNA test (for adult males most effective). In contrast to your common DNA evaluation, African Ancestry's file does not deliver the percentage of DNA this is more likely to have originated across more than a few areas. as a substitute, African Ancestry claims to trace your DNA to a particular area of Africa. 

    according to consultants, despite the fact, African Ancestry's DNA tests come up short. As defined in a weblog submit with the aid of African American genetic genealogist Shannon Christmas, the enterprise's methodology comfortably doesn't analyze a enough number of DNA markers to deliver on its advertising promises. 

    additionally, he writes, "Ethnicity is a complex conception, a concept no longer as rooted in genetics because it is in sociopolitical and cultural constructs. There is no DNA test that may assign any one to an African ethnic neighborhood or what some confer with as an 'African tribe.'" African Ancestry is rarely the best enterprise that claims to be in a position to assess your ethnicity or "ethnic neighborhood of starting place." however its declare to narrow things down to a single "tribe" of origin is overblown, as any African tribe would ostensibly comprise distinct haplogroups. 

    In an electronic mail to CNET, African Ancestry replied: "African Ancestry makes it clear that ethnic agencies are social and cultural groupings, not genetic ones. despite the fact, in response to huge genetic analysis of African lineages carried out with the aid of African Ancestry's co-founder and Scientific Director (who holds a Ph.D. in Biology and focuses on human genetics), we discover that opposite to laymen's beliefs, there are ethnic companies that share genetic lineages. Our results pinpoint genetic lineages that share the identical genetics as our examine takers. Given the mammoth number of lineages in our African Lineage Database, we are in a position to provide the ethnic companies of the individuals with that shared lineage."

    The business's PatriClan check analyzes eight Y-chromosome STRs and the YAP, which it says is a essential identifier for African lineages; and the MatriClan check analyzes three areas of the mitochondrial DNA: HVS1, HVS2 and HVS3. but even though these tests offer reduce-resolution effects than others, African Ancestry's functions are significantly extra costly. The company's Y-DNA check and mtDNA exams can charge $299 each -- otherwise you can take them each, and get an eight-pack of "certificates of ancestry" and a four-pack of t-shirts, for $729. 

    On the plus aspect, African Ancestry says that it doesn't maintain a database of consumer suggestions and that it's going to not share or sell your DNA sequence or markers with any third celebration -- together with legislation enforcement companies. The enterprise's terms and conditions run to simply over 2,200 phrases, making them significantly greater concise than the disclosure statements of most other organizations we blanketed during this roundup. And African Ancestry promises to break your DNA demo after your examine outcomes are delivered.

    That observed, in spite of the fact that you settle for the business's take on tribal and ethnic genetic markers, African Ancestry continues to be too costly to recommend at its present cost.

    DNA testing: What you should understand

    if you're the usage of a home DNA trying out service, you might be likely attempting to find certainly one of three things:

    Ancestry and family unit heritage: the primary big draw of a full DNA look at various is that you can get an in depth breakdown on ancestry and ethnicity, and the migration patterns of your typical ancestors. Spoiler alert: Your ethnic background may be radically distinctive than you think it is. you are going to additionally discover what a haplogroup is.

    Relative identification: along with your permission, some DNA services will will let you join with family you in no way knew you had -- other individuals with matching DNA who've used the provider and likewise given their permission to hook up with viable family members.  

    health and ailment information: DNA trying out can also point out which conditions for which you might also have a preponderance. or not it's a controversial feature, to make certain. realizing that you've a genetic predisposition to a certain sort of cancer can also make you extra vigilant for trying out, nevertheless it may also additionally lead to accelerated stress -- being concerned about a potential health situation that may additionally on no account advance, notwithstanding you might be "genetically prone" to it. The chance of false positives and false negatives abound -- any such suggestions may still be discussed along with your medical professional before you act upon it.

    How DNA tests work

    afraid of needles and drawing blood? good information: it truly is no longer an argument with these checks. All you deserve to do is spit into a vial or rub a swab to your mouth -- all of the genetic statistics needed for these checks is latest for your saliva -- and ship the DNA pattern to the business for analysis. 

    The cause that a saliva pattern works as well as blood (or hair follicles or skin samples) is that your DNA -- which is short for deoxyribonucleic acid -- is present in all of them. or not it's the primary genetic code existing in all your cells that makes up your key attributes, from the color of your eyes to the shape of your ears to how inclined you're to ldl cholesterol.

    The key terms you deserve to comprehend when evaluating DNA checking out capabilities are:

    SNP (single nucleotide polymorphism): Genotyping is done by means of measuring genetic adaptation. one of the crucial extra standard is SNP genotyping, which measures the variations of a single nucleotide polymorphism. The more of those a company measures, the more granular the analysis.

    Autosomal DNA trying out: An autosomal examine this is beneficial for guys and ladies, and which traces lineage again via each maternal and paternal bloodlines.

    Y-DNA: The Y-DNA check can only be administered to men, and traces DNA lower back through the patrilineal ancestry -- definitely from father to grandfather to first rate grandfather and so forth.

    mtDNA: The mtDNA is matrilineal and lets you hint your ancestry lower back through your mom, grandmother, exquisite grandmother and so on. 

    study greater

    David Gewirtz contributed to this story. The current edition is a major update of previous revisions, and includes palms-on impressions of lots of the features listed.

    The information contained in this article is for academic and informational purposes best and is not intended as fitness or medical guidance. all the time consult a doctor or different qualified fitness provider concerning any questions you may additionally have about a medical situation or fitness targets.

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